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Trametinib

Also known as Mekinist (us)

Cancer & Oncology
Save $9,943/mo
6× cheaper

Trametinib is used alone or in combination with dabrafenib (Tafinlar) to treat certain types of melanoma (a type of skin cancer). It is also used in combination with dabrafenib to prevent the return of a certain type of melanoma after surgery.

United States
$11,972
per month
India
$2,028
per month
You save
$9,943
83% cheaper in India
14.5K US scripts/yr$144.4M potential annual savings$173.9M US spend/yr
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Compare the price
US price$11,972per month
India price$2,028per month
You save$9,94383% less

Based on 30 units per month. US $399.06 vs India $67.61 per unit.

Total over 1 periodSave $9,943$11,972 → $2,028
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$59,661
Estimated travel cost
− $2,300
Net savings after travel
$57,361

Even after travel, you could come out ahead by about $57,361.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Trametinib is filled about 14.5K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$173.9M
If sourced from India
$29.5M
Potential annual savings
$144.4M
−83%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.