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Sacubitril / Valsartan

Also known as Entresto (us), Vymada (india)

Heart & Blood Pressure
Save $684/mo
20× cheaper

A combination medicine for chronic heart failure.

United States
$720
per month
India
$36
per month
You save
−95%
save $684/mo · 95% cheaper
3.9M US scripts/yr$2.7B potential annual savings$2.8B US spend/yr
Building 3D structure…
Drag to rotate · 3D structureC48H58N6O8

SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O.CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O

Compare the price
US price$720per month
India price$36per month
You save$68495% less

Based on 60 tablets per month. US $12.00 vs India $0.60 per tablet.

Total over 1 periodSave $684$720$36
The bigger picture

Sacubitril / Valsartan is filled about 3.9M times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$2.8B
If sourced from India
$140.4M
Potential annual savings
$2.7B
95%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.