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Rifaximin

Also known as Xifaxan (us), Rifagut (india)

Digestive & Gut
Skin & Dermatology
Save $1,624/mo
785× cheaper

Rifaximin is used to treat traveler's diarrhea caused by certain bacteria, hepatic encephalopathy (changes in how a person thinks, acts, or feels because their liver is not working properly to remove toxins) and irritable bowel syndrome (with diarrhea).

United States
$1,626
per month
India
$2
per month
You save
$1,624
99.87% cheaper in India
416.7K US scripts/yr$676.5M potential annual savings$677.4M US spend/yr
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Compare the price
US price$1,626per month
India price$9per month
You save$1,61699.42% less

Based on 30 units per month. US $54.19 vs India $0.31 per unit.

Total over 1 periodSave $1,616$1,626 → $9
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$9,697
Estimated travel cost
− $2,300
Net savings after travel
$7,397

Even after travel, you could come out ahead by about $7,397.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Rifaximin is filled about 416.7K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$677.4M
If sourced from India
$862.5K
Potential annual savings
$676.5M
−100%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.