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MedCompare

Plecanatide

Digestive & Gut
Save $516/mo
20× cheaper

TRULANCE is indicated in adults for the treatment of: chronic idiopathic constipation (CIC). irritable bowel syndrome with constipation (IBS-C).

United States
$543
per month
India
$28
per month
You save
−95%
save $516/mo · 95% cheaper
155.1K US scripts/yr$80M potential annual savings$84.3M US spend/yr
Building 3D structure…
Drag to rotate · 3D structureC65H104N18O26S4

SMILES: C[C@H]1C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C(C)C)CC(=O)N)C(C)C)CC(C)C)CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)N)N

Compare the price
US price$543per month
India price$28per month
You save$51695% less

Based on 30 units per month. US $18.11 vs India $0.92 per unit.

Total over 1 periodSave $516$543 → $28
The bigger picture

Plecanatide is filled about 155.1K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$84.3M
If sourced from India
$4.3M
Potential annual savings
$80M
−95%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.