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Palbociclib

Also known as Ibrance (us), Palbace (india)

Cancer & Oncology
Save $15,409/mo
71× cheaper

A CDK4/6 inhibitor used with hormone therapy for HR-positive, HER2-negative advanced breast cancer.

United States
$15,629
per month
India
$221
per month
You save
$15,409
99% cheaper in India
131.5K US scripts/yr$2B potential annual savings$2.1B US spend/yr
Building 3D structure…
Drag to rotate · 3D structureC24H29N7O2

SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C

Compare the price
US price$15,62928-day cycle
India price$22128-day cycle
You save$15,40999% less

Based on 21 capsules 28-day cycle. US $744.24 vs India $10.50 per capsule.

Total over 1 periodSave $15,409$15,629$221
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$92,451
Estimated travel cost
− $2,300
Net savings after travel
$90,151

Even after travel, you could come out ahead by about $90,151.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Palbociclib is filled about 131.5K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$2.1B
If sourced from India
$29M
Potential annual savings
$2B
99%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.