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Macitentan

Also known as Opsumit (us)

Heart & Blood Pressure
Save $12,534/mo
168× cheaper

Macitentan is used to manage the symptoms of pulmonary arterial hypertension (PAH; high blood pressure in the blood vessels that carry blood to the lungs).

United States
$12,609
per month
India
$75
per month
You save
$12,534
99.40% cheaper in India
97.1K US scripts/yr$1.2B potential annual savings$1.2B US spend/yr
Building 3D structure…
Drag to rotate · 3D structureC19H20Br2N6O4S

SMILES: CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br

Compare the price
US price$12,609per month
India price$75per month
You save$12,53499.40% less

Based on 30 units per month. US $420.29 vs India $2.50 per unit.

Total over 1 periodSave $12,534$12,609 → $75
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$75,202
Estimated travel cost
− $2,300
Net savings after travel
$72,902

Even after travel, you could come out ahead by about $72,902.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Macitentan is filled about 97.1K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$1.2B
If sourced from India
$7.3M
Potential annual savings
$1.2B
−99%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.