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Ledipasvir / Sofosbuvir

Also known as Harvoni (us), Ledifos (india)

Hepatitis & Antivirals
Infections
Save $12,329/mo
79× cheaper

The combination of ledipasvir and sofosbuvir is used alone or in combination with ribavirin (Copegus, Rebetol, Ribasphere, others) to treat certain types of chronic hepatitis C (an ongoing viral infection that damages the liver) in adults and children 3 years of age and older.

United States
$12,486
per month
India
$158
per month
You save
$12,329
99% cheaper in India
1.4K US scripts/yr$17.4M potential annual savings$17.6M US spend/yr
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Compare the price
US price$12,486per month
India price$158per month
You save$12,32999% less

Based on 30 units per month. US $416.20 vs India $5.25 per unit.

Total over 1 periodSave $12,329$12,486$158
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$73,972
Estimated travel cost
− $2,300
Net savings after travel
$71,672

Even after travel, you could come out ahead by about $71,672.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Ledipasvir / Sofosbuvir is filled about 1.4K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$17.6M
If sourced from India
$222.3K
Potential annual savings
$17.4M
99%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.