Skip to content

Denosumab

Also known as Prolia (us), Denfova (india)

Bone & Joint
Save $45,731/mo
8× cheaper

Denosumab injection is used to treat certain cases of osteoporosis (a condition in which the bones become thin and weak and break easily) to treat bone loss in individuals with prostate cancer or breast cancer who are being treated with certain medications that cause bone loss to reduce the risk of…

United States
$52,315
per month
India
$6,584
per month
You save
$45,731
87% cheaper in India
468.5K US scripts/yr$21.4B potential annual savings$24.5B US spend/yr
Compare the price
US price$52,315per month
India price$6,584per month
You save$45,73187% less

Based on 30 MLs per month. US $1,743.82 vs India $219.46 per ML.

Total over 1 periodSave $45,731$52,315$6,584
Is travelling to India worth it?

The savings here are large enough that a trip may still come out ahead. Adjust the numbers to your own situation — every value is an editable estimate.

Medicine savings over 6 months
$274,386
Estimated travel cost
− $2,300
Net savings after travel
$272,086

Even after travel, you could come out ahead by about $272,086.

Assumptions: medicine savings = (US − India monthly price) × months. Travel cost = flights + hotel × nights + buffer. Excludes consultation fees, visas, and other costs. For information only — not medical, legal, or travel advice.

The bigger picture

Denosumab is filled about 468.5K times a year under Medicare Part D. At the prices above, that works out to roughly:

Est. annual US spend
$24.5B
If sourced from India
$3.1B
Potential annual savings
$21.4B
87%

Rough estimate. Based on Medicare Part D prescription volume (not the entire US market) scaled by the representative monthly price — actual totals depend on dose, duration and coverage.